FORMAT OF THE MEETING

GIF 2017 will follow the traditional form of a closed meeting for the invitees and will facilitate free/confidential discussions on the topics, as listed below.

Following the introductions, experienced, longstanding GIF members will chair the proposed topic discussions in key areas of glioma invasion, at which everybody else will be expected to contribute verbally or with a few slides by prior arrangement with the nominated chairs.

PhD students and younger investigators are particularly welcomed, as GIF offers the opportunity for student/researcher exchange between different international laboratories.

PROPOSED FORUM TOPICS

*SESSION CONVENOR

(Contributions are welcomed from ALL delegates; please liaise with the convenor of each session and provide him/her with a few slides to accompany your contribution)

Each Session is organised as 2-3 key lectures (circa 15 to maximum-20 min) to introduce the topic of the session  and  suggested short contribution as indicated (circa 7 min) to leave enough time for  free discussion by all participants interested in the theme.

 

Sunday, April 23rd

15:00 – 15:15

*Tamara Lah:  Welcome to GIF 2017

 

15:15 – 16:15    SESSION I - INTRODUCTION

*Geoff Pilkington, University of Portsmouth, Brain Tumour Research Centre, University of Portsmouth, UK:

 How far have we come in understanding glioma invasion; orchestration of CAMs, ECM, Proteases and Cytoskeletal dynamics but what else?

 

GENERAL DISCUSSION

 

16:15 – 18:00  SESSION II - IS IT ALL IN THE GENES?

KEY LECTURE

*Sen Peng, Translational Genomics Research Institute (TGen), Phoenix, Arizona, USA:

Bioinformatics and gene profiling of gloima invasion

 

SHORTER CONTRIBUTIONS

Anbarasu Lourdusamy, Nottingham University, Nottingham, UK:

Transcriptome analysis reveals unique biology of glioblastoma invasive margins

 

GENERAL DISCUSSION

 

19:00 Welcome dinner at Hotel Histrion - Portorož

 

Monday, April 24th

 09:00 – 10:15  SESSION III - PROTEASE AND OTHER SIGNALLING PATHWAYS

KEY LECTURE

*Tamara Lah, Department of Genetic Toxicology and Cancer Biology ,National Institute of Biology, Ljubljana, Slovenia:

 Proteases in GBM invasion and glioma stem cell niche function

 

SHORTER CONTRIBUTIONS

Barbara Breznik, National Institute of Biology, Ljubljana, Slovenia:

Mesenchymal stem cells affect the invasion of GBM cells

 

Patricia Madureira, University of Algarve, Centre for Biomedical Research, Portugal:

The role of the plasminogen system in glioma invasion

 

KEY LECTURE

Mark Gumbleton, School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff,  UK::

Microglial cells and glioma invasion

 

10:15 – 10:45 - COFFEE BREAK

 

10:45 – 12:30  SESSION IV - GLIOMA CELLS ARE NEVER ALONE!

KEY LECTURE

*Christel Herold-Mende, Dept of Neurosurgery University of Heidelberg, Germany:

Glioma micro-environment

 

SHORTER CONTRIBUTIONS

Rolf Warta,  University of Heidelberg, Experimental, Heidelberg, Germany:

Biophysics of neoplastic cell invasion in the brain

 

 Valerie Ferrer, Paulo Niemeyer State Brain Institute, Rio de Janeiro, Brasil:

Chemokine profile comparison in differentiation into and GBM stem cells

 

KEY LECTURE

Reiner Glass, University Clinics Munich, Neurosurgical Research, München, Germany:

A previously unrecognized pericyte progenitor cell promotes glioma angiogenesis and expansion

 

SHORTER CONTRIBUTIONS

Ann-Christine Hau, Luxembourg Institute of Health Neuro-oncology, Luxembourg:

Tumor heterogeneity and evolution in the context of therapy-associated resistance

 

 Daniella Cesselli, Antonio Beltrami, Miran Skrap, Istituto di Anatomia Patologica Azienda Ospedaliero Universitaria University of Udine,  Italy:

Glioma-associated stem cells predict prognosis of human low-grade gliomas

 

13:00 – 14:00 BUFFET LUNCH

 

14:00 - 15:45  SESSION V - THE ORIGIN OF EVIL

KEY LECTURE

*Stephen Minger, SLM Blue Skies Innovations Ltd, London, UK

Innovations in treatment of brain disorders

 

SHORTER CONTRIBUTION

Robert Zorec, Celica, Biomedical Center & University of Ljubljana, Medical School, Slovenia:

Astrocytes in health and disease

 

KEY LECTURE

Rolf Bjerkvig, University of Bergen,  KG-Jebsen Brain Tumour Research Centre Department of Biomedicine,Bergen, Norway:

Cancer stem cells and metabolism

 

16:00 – 16:30 - COFFEE BREAK

 

16:30 – 18:0SESSION VI - PROTEIN FUNCTIONS MAKE THE FINAL DECISION?

 KEY LECTURE

* Franz Ricklefs, University Medical Center Hamburg-Eppendorf, Germany:  

Extracellular Vesicles in brain tumor biology and their role in invasion

 

Radovan Komel, University of Ljubljana, Faculty of Medicine, Ljubljana Slovenia:

GBM proteomic biomarkers identified by reverse proteomics and targeting with nanobodies

 

GENERAL DISCUSSION

 

19:00  - Dinner - Trip to Marezige, Restaurant Karjola

 

Tuesday, April 25th

 09:00 – 10:45  SESSION VII - MODELING GLIOMA INVASION IN VITRO AND IN VIVO

*Mark Gumbleton, School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff,  UK

 

KEY LECTURE

Ruman Rahman, Children's Brain Tumour Research Centre, School of Medicine, University of Nottingham, Nottingham, UK:

Genetic and metabolic signature of the glioma margin

 

SHORTER CONTRIBUTION

Chiara Moriconi, Cardiff University, Cardiff, UK:

A new means with which to evaluate glioma invasion in vitro

 

Rupert Ecker, Tissue Gnostics GmbH, CEO, Vienna, Austria:

Cytometry imaging

 

GENERAL DISCUSSION

Tadej Strojnik, University Clinics Maribor, Dept. of Neurosurgery, Maribor, Slovenia,

Roman Bošnjak, University Medical Centre,  Dept. of Neurosurgery, Ljubljana, Slovenia, etc.
 

10:45-11:00 COFFEE BREAK

 

11:00 – 12:15  SESSION VIII- WHERE DO WE GO FROM HERE ?

 *Rolf Bjerkvig, University of Bergen, Department of Anatomy and Cell Biology, Bergen, Norway:

Where do we go next in unravelling glioma invasion mechanisms?

 

12.15 - 13.00  SESSION IX: OPEN SESSION FOR DISCUSSION AND FORMULATION OF IDEAS FOR COLLABORATION

 *Rainer Glass, University Clinics Munich, Germany, Neurosurgical Research, München, Germany

Students’ corner: All you wanted to say or did not dare to ask…

Alison Howarth, Marko Vidak, Chiara Marconi, Anne Schuster, Alja Zottel, Katja Kološa, Barabara Beznik, etc.. 

 

Final Discussions: All delegates are asked to provide Rainer with slides representing their ideas/suggestions for integrated research proposals and novel areas of research.

 

13:00 – 14:30 BUFFET LUNCH

 

19:00  Trip to Rodica Wine Cellar –  MORE TO DISCUSS?